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Recommendations

Coronavirus guidance

Guidance to support primary care prescribers and pharmacists is available from the MLCSU Coronavirus guidance resource page. Links are provided to national resources and regional documents produced by MLCSU, RDTC, and SPS for use by Pan Mersey APC, LSCMMG, and GMMMG.

The list of resources will be updated as new material becomes available so please check back regularly for updates.

The Pan Mersey APC supports the use of COVID-specific guidance issued by NICE, and NHS England and NHS Improvement. During the COVID pandemic this will supersede any APC advice. In the absence of any COVID-specific advice then the usual Pan Mersey guidance and RAG rating will still apply unless otherwise indicated.

This section contains a list of the policy recommendations of the Pan Mersey Area Prescribing Committee.

Reviews of the new medicines have been conducted by our pharmacists using a number of resources including National Institute for Health and Clinical Excellence (NICE) which is a Special health Authority (SHA) set up in 1999. It is used to give advice to the NHS on best clinical practice including the clinical and cost effectiveness of drugs and other treatments.

Definitions and Criteria for Categorisation of Medicines

Documents

Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of abatacept infusion and subcutaneous injection (Orencia ®) for rheumatoid arthritis and infusion for polyarticular juvenile idiopathic arthritis as described below.

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Date Added: 30 - Nov - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of oral acetylcysteine in idiopathic pulmonary fibrosis.

Body System:
Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of adalimumab injection (Humira®) for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, polyarticular juvenile idiopathic arthritis and in patients fitting other criteria commissioned by Pan Mersey CCGs, as described.

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Date Added: 07 - Jul - 2016

The Pan Mersey Area Prescribing Committee recommends the prescribing of ALIROCUMAB (Praluent®▼) by specialists only, for treating primary hypercholesterolaemia and mixed dyslipidaemia in accordance with NICE TA393.

Body System:
Date Added: 26 - Apr - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of ALIROCUMAB solution for injection (Praluent®▼) for reduction of cardiovascular risk in adults with established atherosclerotic cardiovascular disease.

Body System:
Date Added: 30 - Jan - 2020

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of ALISKIREN tablets (Rasilez®).

Body System:
Date Added: 07 - Jun - 2017

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of antioxidant supplements based on the AREDS or AREDS2 formulae for patients with age related macular degeneration.

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Date Added: 25 - Jan - 2017

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of ASCORBIC ACID for any indication, other than scurvy.

Date Added: 24 - Feb - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of AVATROMBOPAG tablets (Doptelet®▼) for treating severe thrombocytopenia in adults with chronic liver disease having planned invasive procedures.

Date Added: 23 - Oct - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of azithromycin following specialist initiation for certain chronic airway conditions in children.

Body System:
Date Added: 25 - Nov - 2015

The Pan Mersey Area Prescribing Committee recommends the prescribing of azithromycin tablets in selected high risk patients, when recommended by a respiratory specialist, for the prevention of exacerbations in COPD and bronchiectasis.

Body System:
Date Added: 24 - Oct - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ORAL BISPHOSPHONATES (alendronic acid, ibandronic acid and risedronate sodium) for treating osteoporosis in accordance with NICE TA464.

Body System:
Date Added: 03 - Mar - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of Blood Glucose Testing Strips in accordance with the supplied guidance.

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Date Added: 24 - Oct - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of BOTULINUM NEUROTOXIN TYPE A injection (Xeomin®) for the treatment of chronic sialorrhoea, in accordance with NICE TA605.

Body System:
Date Added: 29 - Jul - 2015

The Pan Mersey Area Prescribing Committee recommends no more than TWO TREATMENT SESSIONS per YEAR of Botulinum Toxin Type A Injection (Botox®) by specialists for the treatment of severe axillary hyperhidrosis that has not responded to treatment with topical antiperspirants or other antihidrotic treatment, as a potential alternative to surgery.

Body System:
Date Added: 23 - May - 2018

The Pan Mersey Area Prescribing Committee recommends prescribing a maximum of TWO COURSES of botulinum toxin type A injection in the treatment of chronic anal fissure which has not healed despite a minimum course of at least 8 weeks of topical management.

Date Added: 30 - Jan - 2020

The Pan Mersey Area Prescribing Committee recommends the prescribing of BRIMONIDINE TARTRATE Gel (Mirvaso®) for the treatment of moderate to severe, persistent facial erythema associated with rosacea in adults

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Date Added: 02 - Oct - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of BRIVARACETAM tablets/oral solution (Briviact®▼) for adjunctive treatment of focal seizures following initiation by a consultant neurologist.

AMBER patient retained by specialist NHS Wirral CCG

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Date Added: 24 - Jul - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of BRIVARACETAM tablets or oral solution (Briviact®▼) for the treatment of epilepsy in children and adolescents.

Body System:
Date Added: 26 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of BRODALUMAB solution for injection (Kyntheum®▼), by specialists only, for treating plaque psoriasis in accordance with NICE TA511.

Body System:
Date Added: 04 - May - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of BROLUCIZUMAB solution for injection (Beovu®▼) for neovascular (wet) age-related macular degeneration.

Body System:
Date Added: 28 - Nov - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of nebulised colistimethate (Colomycin®), gentamicin or tobramycin for
adult non- cystic fibrosis bronchiectasis patient.

Body System:
Date Added: 04 - Apr - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of BUDESONIDE orodispersible tablets (Jorveza®▼) for eosinophilic oesophagitis.

Date Added: 29 - Oct - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of BUPRENORPHINE prolonged-release injection (Buvidal®) for the treatment of opioid dependence.

Body System:
Date Added: 14 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for allergy and immunology has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 22 - Oct - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of CALCIPOTRIOL 50 micrograms and BETAMETHASONE 500 micrograms per 1 gram cutaneous foam (Enstilar®) for psoriasis vulgaris in adults.

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Date Added: 01 - Nov - 2017

The Pan Mersey Area Prescribing Committee recommends the prescribing of CANAGLIFLOZIN, DAPAGLIFLOZIN and EMPAGLIFLOZIN as combination therapies for the treatment of type 2 diabetes in accordance with NICE guidance.

Body System:
Date Added: 01 - Nov - 2017

The Pan Mersey Area Prescribing Committee recommends the prescribing of CANAGLIFLOZIN, DAPAGLIFLOZIN and EMPAGLIFLOZIN as MONOTHERAPIES as options for treating type 2 diabetes in adults in accordance with NICE TA390.

Body System:
Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of CARIPRAZINE hard capsules (Reagila®▼), following specialist initiation, as a non-first line treatment option for adult patients with predominant negative symptoms of schizophrenia.

Body System:
Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of certolizumab injection (Cimzia®) for rheumatoid arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis and psoriatic arthritis, as well as in patients fitting other criteria commissioned by Pan Mersey CCGs, as listed below.

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Date Added: 22 - May - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of CERTOLIZUMAB PEGOL solution for injection (Cimzia®▼), by specialists only, for moderate to severe plaque psoriasis in accordance with NICE TA574.

Body System:
Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of CICLOSPORIN 1mg/mL eye drops (Verkazia®), by specialists only, for the treatment of severe vernal keratoconjunctivitis (VKC) in children from 4 years of age and adolescents.

Body System:
Date Added: 26 - Sep - 2017

The Pan Mersey Area Prescribing Committee recommends the prescribing of COLESEVELAM HYDROCHLORIDE (Cholestagel®), following specialist initiation, for adult patients with bile acid malabsorption-associated diarrhoea who do not tolerate, or fail to respond to, 1st line treatments.

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Date Added: 23 - Jun - 2015

The Pan Mersey Area Prescribing Committee does not recommend the routine prescribing of ORAL COMBINATION PRODUCTS that are available as the separate constituents.

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Date Added: 14 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for allergy and immunology has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 01 - Nov - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of CO-PROXAMOL tablets.

Body System:
Date Added: 27 - Feb - 2020

The Pan Mersey Area Prescribing Committee recommends the prescribing of DAPAGLIFLOZIN tablets (Forxiga®) WITH INSULIN, for the treatment of type 1 diabetes mellitus in accordance with NICE TA597.

SGLT2 inhibitors to insulin therapy for patients with type 1 diabetes

Body System:
Date Added: 24 - Apr - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of DAPOXETINE tablets (Priligy®) for the treatment of premature ejaculation when recommended by a psychosexual service or a specialist clinician with experience of treating psychosexual disorders. Treatment is restricted to three doses per month.

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Date Added: 02 - Oct - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of DEGARELIX SC injection (Firmagon®) following specialist initiation for treating advanced hormone-dependent prostate cancer in people with spinal metastases in accordance with NICE TA404.

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Date Added: 02 - Oct - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of DENOSUMAB solution for injection (Prolia®) for the treatment of bone loss associated with long-term systemic glucocorticoid therapy.

Body System:
Date Added: 08 - Feb - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of DEOXYCHOLIC ACID injection (Belkyra®▼) for submental (under chin) fat.

Body System:
Date Added: 27 - Mar - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of DIENOGEST tablets (Zalkya®▼) for endometriosis.

Date Added: 24 - Oct - 2019

DOACs are recommended as an option for treating and/or preventing recurrent DVT and/or PE where an oral anticoagulant is indicated following specialist initiation.

GREEN for NHS Wirral CCG
Oral Anticoagulants (VKA and DOAC). Guidelines for prescribing, monitoring and management.

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Date Added: 24 - Oct - 2019

DOACs are recommended as treatment options for the prevention of stroke and systemic emboli in non-valvular atrial fibrillation where an oral anticoagulant is indicated.

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Date Added: 24 - Apr - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of DOSULEPIN capsules and tablets.

Body System:
Date Added: 31 - Jan - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of DOXAZOSIN modified release (M/R) tablets (All Brands).

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Date Added: 28 - Nov - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of DOXYLAMINE/PYRIDOXINE gastro-resistant tablets (Xonvea®), as an option for the treatment of nausea and vomiting of pregnancy

Body System:
Date Added: 09 - Nov - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of Dupilumab solution for injection (Dupixent®▼), by specialists only, for the treatment of moderate to severe atopic dermatitis in adults in accordance with NICE TA534.

Body System:
Date Added: 28 - Nov - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of DUPILUMAB solution for injection (Dupixient®▼) for the treatment of chronic rhinosinusitis.

Body System:
Date Added: 05 - Oct - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of E - Cigarettes, except as part of Local Authority commissioned Stop Smoking Service arrangements.

Body System:
Date Added: 31 - Oct - 2017

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of EFLORNITHINE 11.5% Cream (Vaniqa®) for hirsutism.

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Date Added: 19 - Jul - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of Elasticated Viscose Stockinette (‘Viscose’) Garments following specialist recommendation for skin conditions.

Body System:
Date Added: 25 - Sep - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of electromagnetic pulse therapy (Actipatch®) for pain relief.

Body System:
Date Added: 23 - May - 2017

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of ELTROMBOPAG tablets (Revolade®) for Acquired Severe Aplastic Anaemia (SAA).

Date Added: 31 - Jan - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ELTROMBOPAG OLAMINE tablets (Revolade®) by Haematologists only, for chronic ITP in accordance with NICE TA293.

Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of ELUXADOLINE Tablets (Truberzi®▼) following specialist initiation for irritable bowel syndrome with diarrhoea in adults in accordance with NICE TA471.

Red NHS West Lancashire CCG

Date Added: 01 - Oct - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of ERENUMAB pre-filled syringes (Aimovig®▼) for prophylaxis of migraine.

Body System:
Date Added: 27 - Mar - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ERTUGLIFLOZIN film-coated tablets (Steglatro®▼) as monotherapy or with metformin for treating type 2 diabetes in accordance with NICE TA572.

Body System:
Date Added: 26 - Jun - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ERTUGLIFLOZIN film-coated tablets (Steglatro®▼) in a triple therapy regimen for treating type 2 diabetes in accordance with NICE TA583.

Body System:
Date Added: 24 - Feb - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of ESKETAMINE nasal spray solution (Spravato®▼) for treatment-resistant depression.

Body System:
Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of etanercept injection for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, polyarticular juvenile idiopathic arthritis and adult-onset Still’s disease, as well as in patients fitting other criteria commissioned by Pan Mersey CCGs, as listed.

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Date Added: 26 - Jun - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of EVOLOCUMAB injection (Repatha SureClick®▼) for reduction of cardiovascular risk in adults with established atherosclerotic cardiovascular disease.

Body System:
Date Added: 30 - Mar - 2016

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of EZETIMIBE (Ezetrol®) for the prevention of cardiovascular events in patients with cholesterol levels within target range.

Body System:
Date Added: 28 - Feb - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of FERRIC MALTOL (Feraccru®) following specialist initiation for the treatment of iron deficiency anaemia in adult patients with inflammatory bowel disease.

Date Added: 21 - Jun - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of FERRIC MALTOL hard capsules (Feraccru®) for the treatment of iron deficiency in adults.

Date Added: 28 - Mar - 2018

The Pan Mersey Area Prescribing Committee recommends
FINASTERIDE 5mg tablets as the 5-alpha reductase inhibitor of choice for men with lower urinary tract symptoms (LUTS) as detailed.

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Date Added: 31 - Jul - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing on the NHS of flash glucose monitor sensors (FreeStyle Libre®) only within the criteria outlined.

These templates should be used by Pan Mersey organisations for incorporation into their specialist diabetes service clinic documentation that informs primary care prescriber that Freestyle Libre prescribing has been initiated in an individual patient according to the agreed criteria in the Pan Mersey statement, when confirming to primary care prescriber whether the patient has met continuation criteria after review, and into patient information/ contract documentation given to each patient on commencement of prescribing.

Initiation Criteria

Continuation Criteria

Primary Care Information

Patient Contract

Body System:
Date Added: 14 - Nov - 2017

The Pan Mersey Area Prescribing Committee recommends the use of FLUENZ®▼ nasal spray in accordance with the Annual flu programme from Public Health England.

Body System:
Date Added: 30 - Jan - 2020

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of FLUOCINOLONE intravitreal implant (Iluvien®) for treating chronic diabetic macular oedema in phakic eyes after an inadequate response to previous therapy, in accordance with NICE TA613

Body System:
Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of FLUOCINOLONE intravitreal implant (Iluvien®), by specialists only, for the treatment of recurrent non-infectious uveitis in accordance with NICE TA590.

Body System:
Date Added: 30 - Jan - 2020

The Pan Mersey Area Prescribing Committee recommends the prescribing of FreeStyle Optium® blood glucose and FreeStyle Optium® ß-ketone test strips only for use with FreeStyle Libre® specifically in patients who are using carbohydrate counting/ bolus advice.

Body System:
Date Added: 25 - Jul - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of FREMANEZUMAB pre-filled syringe for injection (Ajovy®▼) for prophylaxis of migraine.

Body System:
Date Added: 28 - Feb - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of FULVESTRANT solution for injection (Faslodex®) for untreated locally advanced or metastatic oestrogen-receptor positive breast cancer, in accordance with NICE TA503.

Body System:
Date Added: 25 - Jul - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of GALCANEZUMAB solution for injection (Emgality®▼) for prophylaxis of migraine.

Body System:
Date Added: 24 - Apr - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of DPP-4 inhibitors in accordance with NG28-Type 2 diabetes in adults: management.

Body System:
Date Added: 27 - Jul - 2016

The Pan Mersey Area Prescribing Committee recommends the prescribing of GLP-1 mimetics in combination with insulin for type 2 diabetes, only with specialist care advice and ongoing support from a consultant-led MDT.

Body System:
Date Added: 13 - Feb - 2013

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of GLUCOSAMINE products with or without CHONDROITIN.

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Date Added: 31 - Jan - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of golimumab injection (Simponi®), by specialists only, for non-radiographic axial spondyloarthritis in accordance with NICE TA497.

Body System:
Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of golimumab injection (Simponi®) for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, and in patients fitting other criteria commissioned by Pan Mersey CCGs, as listed.

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Date Added: 09 - Nov - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of GUSELKUMAB solution for injection (Tremfya®▼) in specialist settings only, for treating plaque psoriasis in accordance with NICE TA521.

Body System:
Date Added: 11 - Sep - 2013

The Pan Mersey Area Prescribing Committee does not recommend the routine use of HYALURONAN intra-articular injections in the treatment of osteoarthritis.

Body System:
Date Added: 14 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for allergy and immunology has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of infliximab infusion for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis and adult-onset Still’s disease, as well as in patients fitting other criteria commissioned by Pan Mersey CCGs, as listed.

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Date Added: 27 - Feb - 2020

The Pan Mersey Area Prescribing Committee recommends the prescribing of INSULIN DEGLUDEC 100units/mL and 200 units/mL solution for subcutaneous injection (Tresiba®), initiated by specialists only, for type 1 and type 2 diabetes for specific patient groups, taking into account NICE guidance

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Date Added: 26 - Jun - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ITRACONAZOLE, for allergic bronchopulmonary aspergillosis.

Date Added: 31 - Jan - 2018

Ivabradine has been approved by NICE (TA 267)1 as an option for treating chronic heart failure following specialist initiation in patients with chronic, stable heart failure (NYHA class II-IV), left ventricular systolic dysfunction (LVEF 35% or less) and who are in sinus rhythm with a heart rate of 75 beats per minute or more.

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Date Added: 14 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for cystic fibrosis has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 30 - Nov - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of IVERMECTIN 10mg/g cream (Soolantra®) for second line topical treatment of moderate to severe papulopustular rosacea in adult patients.

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Body System:
Date Added: 24 - May - 2017

The Pan Mersey Area Prescribing Committee recommends the prescribing of IXEKIZUMAB solution for injection (Taltz®▼) in specialist settings only, for treating plaque psoriasis in accordance with NICE TA442.

Body System:
Date Added: 02 - Oct - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of IXEKIZUMAB subcutaneous injection (Taltz®▼), by specialists only, for active psoriatic arthritis in adults after inadequate response to DMARDs in accordance with NICE TA537.

Body System:
Date Added: 27 - Mar - 2019

The Pan-Mersey Area Prescribing Committee recommends that Lactase Enzyme Drops 50,000 units/g (Colief®) are not prescribed on the NHS. Patients are advised to purchase Colief® if they wish.

Date Added: 28 - Feb - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of LESINURAD 200mg TABLETS (Zurampic®▼) for treating chronic hyperuricaemia in people with gout in accordance with NICE TA506 [7th February 2018]

Body System:
Date Added: 01 - Oct - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of lidocaine plaster 5% (Ralvo®, Versatis®), except in limited circumstances outlined.

Body System:
Date Added: 31 - Jan - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of LIRAGLUTIDE (Saxenda®▼) 6mg/ml solution for subcutaneous injection for weight management.

Body System:
Date Added: 21 - Jun - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of LOXAPINE inhalation powder (Adasuve®▼) for mild-to-moderate agitation in adult patients with schizophrenia or bipolar disorder.

Body System:
Date Added: 30 - Jan - 2020

The Pan Mersey Area Prescribing Committee recommends the prescribing of LUSUTROMBOPAG tablets (Mulpleo®▼), by specialists only, for treating severe thrombocytopenia in adults with chronic liver disease having planned invasive procedures in accordance with NICE TA617

Date Added: 12 - Mar - 2013

The Pan Mersey Area Prescribing Committee recommends the prescribing of MELATONIN 2mg modified release tablets (Circadin®) 'off-label' for adults aged 18 years and over with a learning disability OR who have been transferred from paediatric services, following specialist initiation in childhood for the treatment of persistent chronic sleep disorders.

AMBER INITIATED in NHS Halton CCG

Body System:
Date Added: 11 - Apr - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of MELATONIN prolonged-release tablets (Slenyto®) for the treatment of insomnia in children with neurodevelopmental conditions.

Body System:
Date Added: 02 - Jul - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of MELATONIN tablets 3 mg and oral solution 1 mg/ml for jet-lag.

Body System:
Date Added: 14 - Nov - 2017

The Pan Mersey Area Prescribing Committee recommends the use of meningococcal group B vaccine (Bexsero)®▼ in accordance with the meningococcal B (MenB) vaccination programme from Public Health England.

Body System:
Date Added: 28 - Feb - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of Mesalazine oral formulations by brand name following specialist initiation for inflammatory bowel disease. Octasa® brand is considered to be equivalent to Asacol® brand and currently represents a more cost effective choice.

Date Added: 30 - Nov - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of methadone tablets (Physeptone®) in adults following initiation by a consultant in pain medicine in a tertiary centre.

 Red  NHS Halton CCG

Prescribing support information

GP letter

Body System:
Date Added: 30 - Jan - 2020

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of MINOCYCLINE for acne.

Body System:
Date Added: 10 - Jul - 2013

The Pan Mersey Area Prescribing Committee recommends the prescribing of MIRABEGRON prolonged-release tablets (Betmiga®▼) for overactive bladder syndrome (OAB) in accordance with NICE TA290.

Body System:
Date Added: 16 - Jan - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of NALDEMEDINE tablets (Rizmoic®▼) for the treatment of opioid-induced constipation.

Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of NALMEFENE (Selincro®) within its marketing authorisation, as an option for reducing alcohol consumption in adults with alcohol dependence, in line with NICE TA325.

Refer to Pan Mersey formulary for RAG status for each individual CCG.

Body System:
Date Added: 28 - Jul - 2015

The Pan Mersey Area Prescribing Committee recommends the prescribing of NALOXEGOL Tablets (Moventig®▼) as an option for treating opioid induced constipation in adults in accordance with NICE TA345 (22nd July 2015).

Static

Date Added: 31 - Jan - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of NALTREXONE-BUPROPION 8 mg/90 mg prolonged-release tablets (Mysimba®▼) for managing overweight and obesity in accordance with NICE TA494.

Body System:
Date Added: 19 - Dec - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of NICOTINE inhaler (Voke®) for nicotine dependence.

Body System:
Date Added: 31 - Jul - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of CONJUGATED OESTROGENS and BAZEDOXIFENE 0.45mg/20mg modified release tablets (Duavive®) for the treatment of oestrogen deficiency in postmenopausal women with a uterus.

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Body System:
Date Added: 31 - Jul - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of OPICAPONE (Ongentys®▼) following specialist recommendation as add-on therapy in adult patients with Parkinson’s disease.

BLACK NHS West Lancashire CCG

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Body System:
Date Added: 21 - Jun - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of OSPEMIFENE film-coated tablets (Senshio®▼) for the treatment of vulvar and vaginal atrophy in post-menopausal women.

Body System:
Date Added: 01 - Nov - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of OXYCODONE with NALOXONE modified release tablets (Targinact®) for adults with chronic pain

Body System:
Date Added: 24 - Jun - 2015

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of OXYCODONE with NALOXONE modified release tablets (Targinact®) for restless legs syndrome.

Body System:
Date Added: 30 - Mar - 2020

The Pan Mersey Area Prescribing Committee recommends the prescribing of PATIROMER powder for oral suspension (Veltassa®▼) for emergency treatment of life-threatening hyperkalaemia in adults in accordance with NICE TA623.

Date Added: 30 - Mar - 2020

The Pan Mersey Area Prescribing Committee recommends the prescribing of PATIROMER powder for oral suspension (Veltassa®▼) for persistent hyperkalaemia in adults following initiation by a specialist in accordance with NICE TA623.

Date Added: 28 - Nov - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of PENTOSAN POLYSULFATE SODIUM capsules (Elmiron®), by specialists only, for treating bladder pain syndrome in accordance with NICE TA610.

Body System:
Date Added: 05 - Oct - 2018

The Pan Mersey Area Prescribing Committee recommends generic sildenafil as the first choice phosphodiesterase type-5 inhibitor for the treatment of erectile dysfunction.

Body System:
Date Added: 27 - Mar - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of PITOLISANT tablets (Wakix®▼), by specialists working in a regional and national tertiary commissioned sleep service only, for the treatment of Narcolepsy with or without cataplexy in those who are contraindicated or have not tolerated other standard treatments.

Black NHS West Lancashire CCG

Body System:
Date Added: 26 - Jun - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of voriconazole or posaconazole, by GPs or specialists, for Allergic Bronchopulmonary Aspergillosis.

Date Added: 24 - May - 2018

The Pan-Mersey Area Prescribing Committee does not recommend the prescribing of Potassium Hydroxide 5% (MolluDab® or Molutrex®) on the NHS. Patients are advised to purchase MolluDab® or Molutrex® if they wish.

Static

Body System:
Date Added: 26 - Apr - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of PRASTERONE pessaries (Intrarosa®▼) for the treatment of vulvar and vaginal atrophy in postmenopausal women having moderate to severe symptoms.

Body System:
Date Added: 08 - Jan - 2015

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of PREDNISOLONE ENTERIC COATED 2.5 mg and 5 mg tablets.

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Date Added: 01 - Oct - 2018

The Pan Mersey Area Prescribing Committee recommends that IMMEDIATE RELEASE QUETIAPINE is the preferred formulation of quetiapine for prescribing across the Pan Mersey Area.

AMBER RETAINED NHS Southport and Formby, NHS South Sefton CCG

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Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of RANIBIZUMAB intravitreal injection (Lucentis®), by ophthalmologists only, for the treatment of visual impairment secondary to choroidal neovascularisation (CNV) in conditions not covered by NICE technology appraisals.

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Date Added: 19 - Dec - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of RANIBIZUMAB solution for injection (Lucentis®) for the treatment of proliferative diabetic retinopathy.

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Date Added: 31 - Jul - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of Rasburicase powder and solvent for concentrate for solution for infusion (Fasturtec®▼) for the “off label” treatment of severe, refractory, tophaceous gout resistant to xanthine oxidase inhibitors (allopurinol & febuxostat) and uricosuric agents (benzbromarone) or for whom these drugs are contraindicated.

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Date Added: 26 - Jul - 2017

The Pan Mersey Area Prescribing Committee recommends RIFAXIMIN 550mg tablets (Targaxan®), following specialist initiation, as an option for reducing the recurrence of overt hepatic encephalopathy in people aged 18 years or older in accordance with NICE TA 337.

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Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of RISANKIZUMAB solution for injection (Skyrizi®▼), by specialists only, for moderate to severe plaque psoriasis in accordance with NICE TA596.

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Date Added: 15 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for specialised rheumatology has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 15 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for specialised rheumatology has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 26 - Jun - 2019

RITUXIMAB (Truxima®▼, Rixathon®▼)The Pan Mersey Area Prescribing Committee recommends the prescribing of rituximab by specialists only, for immune (idiopathic) thrombocytopenic purpura before romiplostin and eltrombopag.

Date Added: 24 - May - 2017

The Pan Mersey Area Prescribing Committee recommends the prescribing of rituximab infusion for rheumatoid arthritis in accordance with NICE TA195 and in accordance with the Mersey Rheumatoid Arthritis Biologics Pathway.  Treatment should be initiated and supervised by a rheumatologist.

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Date Added: 24 - May - 2017

The Pan Mersey Area Prescribing Committee recommends the prescribing of Rivaroxaban 2.5mg tablets (Xarelto®▼) following specialist initiation for preventing adverse outcomes after acute management of acute coronary syndrome in accordance with NICE TA335.

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Date Added: 28 - Nov - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of RIVAROXABAN 2.5mg tablets (Xarelto®▼) plus aspirin, for the prevention of atherothrombotic events in adult patients with coronary artery disease (CAD) or symptomatic peripheral artery disease (PAD) at high risk of ischaemic events, in accordance with NICE TA607.

Body System:
Date Added: 31 - Jul - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ROFLUMILAST tablets (Daxas®▼) following specialist recommendation as an add-on to bronchodilator therapy, for treating severe chronic obstructive pulmonary disease in adults with chronic bronchitis (in accordance with NICE TA461).

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Date Added: 31 - Jan - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ROMIPLOSTIM SC injection (Nplate®), by Haematologists only, for chronic immune (idiopathic) thrombocytopenic purpura (ITP) in accordance with NICE TA221.

Date Added: 06 - May - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of ROMOSOZUMAB solution for injection (EVENITY®▼) for treatment of severe osteoporosis in postmenopausal women.

Body System:
Date Added: 31 - Jan - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of ROSUVASTATIN TABLETS tablets ONLY where no other statin is suitable.

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Date Added: 26 - Jun - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of RUBEFACIENTS (excluding topical NSAIDS and capsaicin).

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Date Added: 24 - Oct - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of SACUBITRIL/VALSARTAN film-coated tablets (Entresto®▼) for treating symptomatic chronic heart failure following specialist initiation and in accordance with NICE TA388.

North West Strategic Clinical Network and Senate

Position statement

Treatment algorithm

Patient information leaflet

GP communication letter

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Date Added: 31 - Jul - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of SAFINAMIDE (Xadago®▼) following specialist recommendation in the management of mid to late stage Parkinson’s disease.

BLACK NHS West Lancashire CCG

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Date Added: 26 - Jun - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of SECUKINUMAB solution for injection (Cosentyx®) for non-radiographic axial spondyloarthritis.

Body System:
Date Added: 29 - Jul - 2015

The Pan Mersey Area Prescribing Committee recommends SECUKINUMAB solution for subcutaneous injection (Cosentyx®▼) for adults with plaque psoriasis only in accordance with NICE TA350.

Body System:
Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of SILK garments (Dermasilk®, Dreamskin®, Skinnies Silk®) for eczema or atopic dermatitis.

Body System:
Date Added: 27 - Mar - 2019

The Pan Mersey Area Prescribing Committee recommends SODIUM OXYBATE oral solution (Xyrem®) as a treatment option for Narcolepsy with cataplexy in adult patients only when recommended by a consultant in a specialist commissioned sleep service.

Black NHS West Lancashire CCG

Body System:
Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of SODIUM ZIRCONIUM CYCLOSILICATE powder for oral suspension (Lokelma®▼) for the treatment of hyperkalaemia, within secondary care only, in line with NICE TA599.

Date Added: 21 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for infectious disease has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 29 - Jul - 2014

The Pan Mersey Area Prescribing Committee does not recommend the routine prescribing of ORAL COMBINATION PRODUCTS that are available as the separate constituents.

Body System:
Date Added: 21 - Nov - 2017

NHS England specialised commissining resources: the clinical reference group responsible for HIV has published a commissioning policy that defines access to a particular service for a cohort of patients.

Body System:
Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of TAPENTADOL immediate release preparations (Palexia®) for pain relief.

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Date Added: 27 - Jun - 2018

The Pan Mersey Area Prescribing Committee recommends TAPENTADOL prolonged release tablets (Palexia® SR) for severe chronic pain in adults only when initiated by chronic pain specialists or palliative care specialists.

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Date Added: 25 - Sep - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of TESTOSTERONE preparations for testosterone deficiency in women.

Body System:
Date Added: 01 - Aug - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of DESICCATED THYROID EXTRACTS, e.g. Armour Thyroid, in the management of hypothyroidism.

Body System:
Date Added: 22 - May - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of TICAGRELOR tablets (Brilique®), following specialist initiation, for the management of acute coronary syndromes in adults in accordance with NICE TA236 and for preventing atherothrombotic events after myocardial infarction in accordance with NICE TA420.

GP support resource

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Date Added: 22 - May - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of TILDRAKIZUMAB solution for injection (Ilumetri®▼), by specialists only, for moderate to severe plaque psoriasis in accordance with NICE TA575.

Body System:
Date Added: 24 - May - 2018

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of TIOTROPIUM inhalation (Spiriva Respimat®▼) for asthma in children and young people < 18 years of age.

Body System:
Date Added: 01 - Nov - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of TIOTROPIUM inhaler (Spiriva® Respimat®) as an option for patients with poorly controlled asthma who are already on a maintenance dose of inhaled corticosteroid plus a long-acting beta2 agonist inhaler.

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Date Added: 11 - Apr - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of tocilizumab infusion and subcutaneous injection  (RoActemra®) for the treatment of rheumatoid arthritis and adult-onset Still’s disease, and the infusion for juvenile idiopathic arthritis, as described.

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Date Added: 31 - Jan - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of TOFACITINIB film-coated tablets (Xeljanz®▼), by specialists only, for moderately to severely active Ulcerative Colitis in accordance with NICE TA547.

Date Added: 30 - Nov - 2018

The Pan Mersey Area Prescribing Committee recommends the prescribing of TOFACITINIB tablets (Xeljanz®▼), by specialists only, for treating psoriatic arthritis after inadequate response to DMARDs in accordance with NICE TA543.

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Date Added: 22 - May - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of TOLVAPTAN tablets (Samsca®), by specialists only, for the treatment of hyponatraemia secondary to SIADH due to any cause.

Body System:
Date Added: 04 - Jun - 2018

The Pan Mersey Area Prescribing Committee does not recommend the routine prescribing of ORAL COMBINATION PRODUCTS that are available as the separate constituents.

Body System:
Date Added: 24 - Apr - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of TRIMIPRAMINE capsules and tablets.

Body System:
Date Added: 28 - Feb - 2018

The Pan Mersey Area Prescribing Committee recommends that TRIPTORELIN (Decapeptyl® SR 3mg, 11.25mg and 22.5mg) INTRAMUSCULAR INJECTION is first choice gonadorelin analogue for prostate cancer following specialist urologist / oncologist initiation under applicable local arrangement.

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Date Added: 31 - Jan - 2019

The Pan Mersey Area Prescribing Committee recommends the prescribing of ULIPRISTAL ACETATE tablets (Esmya®), by physicians experienced in the diagnosis and treatment of uterine fibroids, in line with the prescribing criteria defined.

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Date Added: 24 - Feb - 2020

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of UPADACITINIB prolonged-release tablets (RINVOQ®▼) for treating moderate to severe rheumatoid arthritis.

Body System:
Date Added: 24 - May - 2017

The Pan Mersey Area Prescribing Committee recommends the prescribing of USTEKINUMAB injection (Stelara®) for active psoriatic arthritis in accordance with NICE TA340.

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Date Added: 18 - Oct - 2019

The Pan Mersey Area Prescribing Committee does not currently recommend the prescribing of USTEKINUMAB solution for injection (Stelara®) for the treatment of moderately to severely active ulcerative colitis.

Date Added: 26 - Jun - 2019

The Pan Mersey Area Prescribing Committee does not recommend the prescribing of voriconazole or posaconazole, by GPs or specialists, for Allergic Bronchopulmonary Aspergillosis.