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Recommendations

This section contains a list of the policy recommendations of the Pan Mersey Area Prescribing Committee.

Reviews of the new medicines have been conducted by our pharmacists using a number of resources including National Institute for Health and Clinical Excellence (NICE) which is a Special health Authority (SHA) set up in 1999. It is used to give advice to the NHS on best clinical practice including the clinical and cost effectiveness of drugs and other treatments.

Definitions and Criteria for Categorisation of Medicines

Documents

Red
ABATACEPT infusion and subcutaneous injection (Orencia®) for Psoriatic Arthritis
Date Posted: 24 - Feb - 2016
Body System: Musculoskeletal system
Red
Abatacept infusion and subcutaneous injection (Orencia®) in rheumatological conditions
Date Posted: 11 - Apr - 2018
Body System: Musculoskeletal system
Grey
ACETYLCYSTEINE for Mucolytic Respiratory Disorders
Date Posted: 13 - Sep - 2018
Body System: Respiratory system
Black
ACETYLECYSTEINE in idiopathic pulmonary fibrosis
Date Posted: 28 - Sep - 2016
Body System: Respiratory system
Red
ADALIMUMAB in the management of Psoriasis
Date Posted: 20 - Jun - 2018
Body System: Skin
Red
ADALIMUMAB injection (Humira®) in rheumatological conditions
Date Posted: 11 - Apr - 2018
Body System: Musculoskeletal system
Red
AFLIBERCEPT intravitreal injection (Eylea®▼) for branch retinal vein occlusion
Date Posted: 02 - Nov - 2016
Body System: Eye
Red
AFLIBERCEPT intravitreal injection (Eylea®▼) for Choroidal Neovascularisation
Date Posted: 23 - Jul - 2018
Body System: Eye
Red
ALIROCUMAB injection (Praluent®▼)
Date Posted: 07 - Jul - 2016
Body System: Cardiovascular system
Black
Antioxidant supplements for Age-Related Macular Degeneration
Date Posted: 07 - Jun - 2017
Body System: Eye
Red
APREMILAST film coated tablets (Otezla®▼) for treating active psoriatic arthritis
Date Posted: 29 - May - 2018
Body System: Musculoskeletal system
Red
APREMILAST film coated tablets (Otezla®▼) for treating moderate to severe plaque psoriasis
Date Posted: 25 - Jan - 2017
Body System: Skin
Black
ASCORBIC ACID
Date Posted: 25 - Jan - 2017
Body System: Blood and blood-forming organs
Amber retained
AZITHROMYCIN oral liquid and tablets – paediatric use
Date Posted: 27 - Sep - 2017
Body System: Anti-infective
Amber recommended
AZITHROMYCIN tablets for prevention of exacerbations of COPD and bronchiectasis in selected high-risk patients
Date Posted: 25 - Nov - 2015
Body System: Respiratory system
Red
BARICITINIB film-coated tablets (Olumiant®▼)
Date Posted: 27 - Sep - 2017
Body System: Musculoskeletal system
Green
BISPHOSPHONATES, oral for treating osteoporosis
Date Posted: 27 - Sep - 2017
Body System: Endocrine System
Green
BLOOD GLUCOSE TESTING STRIPS
Date Posted: 03 - Mar - 2018
Body System: Endocrine System
Red
Botulinum Toxin Type A (Botox®) for Severe Axillary Hyperhidrosis
Date Posted: 29 - Jul - 2015
Body System: Skin
Red
BOTULINUM TOXIN Type A injection for chronic anal fissure
Date Posted: 24 - May - 2018
Body System: Gastro-intestinal system
Green
BRIMONIDINE TARTRATE Gel (Mirvaso®)
Date Posted: 23 - Jul - 2018
Body System: Skin
Amber initiated
BRIVARACETAM tablets and oral solution (Briviact®▼)
Date Posted: 02 - Oct - 2018
Body System: Nervous system
Grey
BRIVARACETAM tablets and oral solution (Briviact®▼) for the treatment of epilepsy in children and adolescents
Date Posted: 24 - Jul - 2018
Body System: Nervous system
Red
BRODALUMAB in the management of Psoriasis
Date Posted: 27 - Jun - 2018
Body System: Skin
Red
BRODALUMAB solution for injection (Kyntheum®▼) for treating plaque psoriasis
Date Posted: 26 - Apr - 2018
Body System: Skin
NHS England
C1-ESTERASE INHIBITOR (Berinert®, Cinryze®▼)
Date Posted: 14 - Nov - 2017
Body System: Immune system
Green
CALCIPOTRIOL and BETAMETHASONE cutaneous foam (Enstilar®)
Date Posted: 28 - Jun - 2017
Body System: Skin
Green
CANAGLIFLOZIN, DAPAGLIFLOZIN and EMPAGLIFLOZIN as COMBINATION THERAPIES : a multiple prescribing statement
Date Posted: 01 - Nov - 2017
Body System: Endocrine System
Green
CANAGLIFLOZIN, DAPAGLIFLOZIN and EMPAGLIFLOZIN as MONOTHERAPIES : a multiple prescribing statement
Date Posted: 01 - Nov - 2017
Body System: Endocrine System
Grey
CANNABIS-BASED products for medicinal use
Date Posted: 01 - Nov - 2018
Body System: Nervous system
Grey
CARIPRAZINE capsules (Reagila®▼) for Schizophrenia in Adults
Date Posted: 02 - Oct - 2018
Body System: Nervous system
Red
CERTOLIZUMAB injection (Cimzia®) in rheumatological conditions
Date Posted: 11 - Apr - 2018
Body System: Musculoskeletal system
Red
CERTOLIZUMAB PEGOL (Cimzia®) and SECUKINUMAB (Cosentyx®▼) in Psoriatic Arthritis
Date Posted: 28 - Jun - 2017
Body System: Skin
Red
CERTOLIZUMAB PEGOL injection (Cimzia®) in rheumatoid arthritis
Date Posted: 30 - Nov - 2016
Body System: Musculoskeletal system
Grey
CERTOLIZUMAB PEGOL solution for injection (Cimzia®) for Plaque Psoriasis
Date Posted: 06 - Sep - 2018
Body System: Skin
Amber initiated
CICLOSPORIN 1mg/mL (0.1%) eye drops, emulsion (Ikervis®)
Date Posted: 27 - Jan - 2016
Body System: Eye
Green
COLECALCIFEROL products, LICENSED ORAL
Date Posted: 25 - Jan - 2017
Body System: Nutrition and metabolic disorders
Amber initiated
COLESEVELAM HYDROCHLORIDE (Cholestagel®)
Date Posted: 27 - Sep - 2017
Body System: Gastro-intestinal system
Red
COLLAGENASE CLOSTRIDIUM HISTOLYTICUM injection (Xiapex®) for Dupuytren’s Contracture
Date Posted: 27 - Sep - 2017
Body System: Musculoskeletal system
Black
COLLAGENASE CLOSTRIDIUM HISTOLYTICUM injection (Xiapex®) for Peyronie's disease
Date Posted: 31 - Jan - 2018
Body System: Genito-urinary system
Black
COMBINATION PRODUCTS, ORAL
Date Posted: 24 - Jun - 2015
Body System: General prescribing advice
NHS England
CONESTAT ALFA (Ruconest®▼)
Date Posted: 14 - Nov - 2017
Body System: Immune system
Black
CO-PROXAMOL tablets
Date Posted: 01 - Nov - 2018
Body System: Nervous system
Amber retained
DAPOXETINE tablets (Priligy®▼)
Date Posted: 27 - Jul - 2016
Body System: Genito-urinary system
Amber retained
DEGARELIX subcutaneous (SC) injection (Firmagon®)
Date Posted: 02 - Oct - 2018
Body System: Gastro-intestinal system
Grey
DENOSUMAB solution for injection (Prolia®) for bone loss associated with long-term systemic glucocorticoid therapy
Date Posted: 02 - Oct - 2018
Body System: Endocrine System
Red
DEXAMETHASONE intravitreal implant (Ozurdex®)
Date Posted: 17 - Sep - 2017
Body System: Eye
Red
DIMETHYL FUMARATE gastro-resistant tablets (Skilarence®)
Date Posted: 27 - Sep - 2017
Body System: Skin
Amber initiated
Direct oral anticoagulants (DOACs) (previously known as NOACs) for the treatment and prevention of Deep Vein Thrombosis (DVT) and/or Pulmonary Embolism (PE)
Date Posted: 26 - Apr - 2018
Body System: Cardiovascular system
Green
Direct Oral Anticoagulants (DOACs) (previously known as NOACs) in Non Valvular Atrial Fibrillation: a multiple prescribing statement for Apixaban, Dabigatran, Edoxaban and Rivaroxaban
Date Posted: 26 - Apr - 2018
Body System: Cardiovascular system
Black
DOXAZOSIN modified release (M/R) tablets (All Brands)
Date Posted: 31 - Jan - 2018
Body System: Cardiovascular system
Grey
DOXYLAMINE/PYRIDOXINE tablets (Xonvea®▼) for Nausea and Vomiting in Pregnancy
Date Posted: 01 - Nov - 2018
Body System: Nervous system
Red
DUPILUMAB solution for injection (Dupixent®▼)
Date Posted: 09 - Nov - 2018
Body System: Skin
Black
E - Cigarettes
Date Posted: 05 - Oct - 2018
Body System: Nervous system
Black
EFLORNITHINE (Vaniqa®) cream
Date Posted: 01 - Nov - 2017
Body System: Skin
Amber recommended
Elasticated Viscose Stockinette (‘Viscose’) Garments (CliniFast®, Comfifast Easywrap®, Skinnies Viscose®, Tubifast 2-way stretch®)
Date Posted: 19 - Jul - 2018
Body System: Skin
Grey
ELECTROMAGNETIC PULSE THERAPY (Actipatch®)
Date Posted: 25 - Sep - 2018
Body System: Nervous system
Black
ELTROMBOPAG film-coated tablets (Revolade®) for Acquired Severe Aplastic Anaemia (SAA)
Date Posted: 24 - May - 2017
Body System: Blood and blood-forming organs
Amber retained
ELUXADOLINE Tablets (Truberzi®▼)
Date Posted: 11 - Apr - 2018
Body System: Gastro-intestinal system
Grey
ERENUMAB pre-filled syringes (Aimovig®▼)
Date Posted: 01 - Oct - 2018
Body System: Nervous system
Red
ETANERCEPET in the management of Psoriasis
Date Posted: 27 - Jun - 2018
Body System: Skin
Red
ETANERCEPT injection (including biosimilars) in rheumatological conditions
Date Posted: 11 - Apr - 2018
Body System: Musculoskeletal system
Grey
EVOLOCUMAB solution for injection (Repatha®▼) for the reduction of cardiovascular risk in patients with established atherosclerotic cardiovascular disease
Date Posted: 21 - Jun - 2018
Body System: Cardiovascular system
Grey
EZETIMIBE (Ezetrol®) for the prevention of cardiovascular events
Date Posted: 30 - Mar - 2016
Body System: Cardiovascular system
Green
FENTANYL transdermal patch - brand choice
Date Posted: 25 - Jan - 2017
Body System: Nervous system
Green
FERRIC MALTOL 30mg hard capsules (Feraccru®) or the treatment of iron deficiency anaemia in adult patients with inflammatory bowel disease
Date Posted: 28 - Feb - 2018
Body System: Blood and blood-forming organs
Grey
FERRIC MALTOL hard capsules (Feraccru®) for iron deficiency in adults
Date Posted: 21 - Jun - 2018
Body System: Blood and blood-forming organs
Green
FINASTERIDE 5mg tablets
Date Posted: 28 - Mar - 2018
Body System: Genito-urinary system
Amber initiated
FLASH GLUCOSE MONITOR (FreeStyle Libre®)
Date Posted: 23 - May - 2018
Body System: Endocrine System
PHE
FLUENZ®▼ nasal spray
Date Posted: 14 - Nov - 2017
Body System: Anti-infective
Black
FULVESTRANT solution for injection (Faslodex®)
Date Posted: 28 - Feb - 2018
Body System: Malignant disease
Grey
GLARGINE + LIXISENATIDE solution for injection (Suliqua®▼)
Date Posted: 14 - Apr - 2017
Body System: Endocrine System
Green
GLIPTINS (Dipeptidylpeptidase-4 [DPP-4] inhibitors)
Date Posted: 27 - Jul - 2016
Body System: Endocrine System
Amber retained
GLP-1 mimetics in combination with insulin
Date Posted: 27 - Jul - 2016
Body System: Endocrine System
Black
GLUCOSAMINE and CHONDROITIN products
Date Posted: 13 - Feb - 2013
Body System: Musculoskeletal system
Red
GOLIMUMAB INJECTION (Simponi®) in non-radiographic axial spondyloarthritis
Date Posted: 31 - Jan - 2018
Body System: Musculoskeletal system
Red
GOLIMUMAB injection (Simponi®) in rheumatological conditions
Date Posted: 11 - Apr - 2018
Body System: Musculoskeletal system
Red
GUSELKUMAB solution for injection (Tremfya®▼) for Plaque Psoriasis
Date Posted: 09 - Nov - 2018
Body System: Skin
Black
HYALURONAN intra-articular injection
Date Posted: 11 - Sep - 2013
Body System: Musculoskeletal system
Green
HYPNOTIC prescribing in Adults
Date Posted: 30 - Sep - 2015
Body System: Nervous system
Green
IBUPROFEN and NAPROXEN (oral formulations)
Date Posted: 25 - Jan - 2017
Body System: Musculoskeletal system
NHS England
ICATIBANT (Firazyr®▼)
Date Posted: 14 - Nov - 2017
Body System: Immune system
Red
INFLIXIMAB in the management of Psoriasis
Date Posted: 27 - Jun - 2018
Body System: Skin
Red
INFLIXIMAB infusion (including biosimilars) in rheumatological conditions
Date Posted: 11 - Apr - 2018
Body System: Musculoskeletal system
Amber initiated
Insulin DEGLUDEC 100units/mL and 200 units/mL solution for subcutaneous injection (Tresiba®▼)
Date Posted: 28 - Feb - 2018
Body System: Endocrine System
Amber initiated
INSULIN, BIOSIMILAR PRODUCTS
Date Posted: 24 - Feb - 2016
Body System: Endocrine System
Amber initiated
INSULIN, HIGH STRENGTH PRODUCTS
Date Posted: 28 - Jun - 2017
Body System: Endocrine System
Amber initiated
IVABRADINE (Procoralan®) for the treatment of chronic heart failure
Date Posted: 31 - Jan - 2018
Body System: Cardiovascular system
NHS England
IVACAFTOR (Kalydeco®▼)
Date Posted: 14 - Nov - 2017
Body System: Respiratory system
Green
IVERMECTIN 10mg/g Cream (Soolantra®▼)
Date Posted: 29 - Mar - 2017
Body System: Skin
Red
IXEKIZUMAB in the management of Psoriasis
Date Posted: 27 - Jun - 2018
Body System: Skin
Red
IXEKIZUMAB solution for injection (Taltz®▼) for Plaque Psoriasis
Date Posted: 24 - May - 2017
Body System: Skin
Red
IXEKIZUMAB solution for injection (Taltz®▼) for Psoriatic Arthritis
Date Posted: 02 - Oct - 2018
Body System: Musculoskeletal system
Black
LACTASE ENZYME drops 50,000 units/g (Colief®)
Date Posted: 25 - Jan - 2017
Body System: Gastro-intestinal system
Black
LESINURAD 200mg tablets (Zurampic®▼)
Date Posted: 28 - Feb - 2018
Body System: Nervous system
Black
Lidocaine plaster 5% (Ralvo®, Versatis®) in adults and children in primary care
Date Posted: 01 - Oct - 2018
Body System: Nervous system
Black
LIRAGLUTIDE (Saxenda®▼) for weight management
Date Posted: 31 - Jan - 2018
Body System: Endocrine System
Grey
LOXAPINE inhalation powder (Adasuve®▼)
Date Posted: 21 - Jun - 2018
Body System: Nervous system
Amber retained
MELATONIN modified release tablets 2mg (Circadin®) ‘off – label’ use in Adults
Date Posted: 12 - Mar - 2013
Body System: Nervous system
PHE
MENINGOCOCCAL GROUP B VACCINE (Bexsero®▼)
Date Posted: 14 - Nov - 2017
Body System: Immune system
Amber initiated
MESALAZINE oral formulations
Date Posted: 28 - Feb - 2018
Body System: Gastro-intestinal system
Green
MIRABEGRON prolonged-release tablets (Betmiga®▼)
Date Posted: 10 - Jul - 2013
Body System: Genito-urinary system
No RAG
NALMEFENE film coated tablets (Selincro®▼)
Date Posted: 27 - Sep - 2017
Body System: Nervous system
Green
NALOXEGOL Tablets (Moventig®▼)
Date Posted: 29 - Jul - 2015
Body System: Gastro-intestinal system
Black
NALTREXONE/BUPRIOPION prolonged-release tablets (Mysimba®▼)
Date Posted: 31 - Jan - 2018
Body System: Nervous system
Black
OESTROGENS, CONJUGATED and BAZEDOXIFENE ACETATE tablets (Duavive®)
Date Posted: 28 - Jun - 2017
Body System: Endocrine System
Amber recommended
OPICAPONE capsules (Ongentys®▼)
Date Posted: 24 - May - 2017
Body System: Nervous system
Grey
OSPEMIFENE film-coated tablets (Senshio®▼)
Date Posted: 21 - Jun - 2018
Body System: Genito-urinary system
Black
OXYCODONE with NALOXONE modified release tablets (Targinact®) for adults with chronic pain
Date Posted: 01 - Nov - 2018
Body System: Nervous system
Grey
OXYCODONE with NALOXONE modified release tablets (Targinact®) for restless legs syndrome
Date Posted: 24 - Jun - 2015
Body System: Nervous system
Grey
PATIROMER powder for oral suspension (Veltassa®▼)
Date Posted: 20 - Oct - 2017
Body System: Cardiovascular system
Green
PHOSPHODIESTERASE TYPE-5 INHIBITORS for the treatment of erectile dysfunction
Date Posted: 05 - Oct - 2018
Body System: Genito-urinary system
Grey
PITOLISANT HYDROCHLORIDE film-coated tablets (Wakix®▼)
Date Posted: 20 - Oct - 2016
Body System: Nervous system
Black
POTASSIUM HYDROXIDE 5% Solution (MolluDab® or Molutrex®)
Date Posted: 24 - May - 2018
Body System: Skin
Black
PREDNISOLONE ENTERIC COATED tablets
Date Posted: 08 - Jan - 2015
Body System: Endocrine System Gastro-intestinal system Musculoskeletal system Respiratory system
Amber initiated
QUETIAPINE Immediate Release I/R Tablets (All Brands)
Date Posted: 01 - Oct - 2018
Body System: Nervous system
Red
RANIBIZUMAB intravitreal injection (Lucentis®) for choroidal neovascularisation
Date Posted: 27 - Sep - 2017
Body System: Eye
Black
RASBURICASE powder and solvent for concentrate for solution for infusion (Fasturtec®▼) for severe, refractory, tophaceous gout
Date Posted: 28 - Jun - 2017
Body System: Musculoskeletal system
Amber retained
RIFAXIMIN 550mg tablets (Targaxan®▼)
Date Posted: 26 - Jul - 2017
Body System: Gastro-intestinal system
NHS England
RITUXIMAB (MabThera®) for the Treatment of Anti-Neutrophil Cytoplasmic Antibody-Associated (ANCA) Vasculitis (AAV)
Date Posted: 15 - Nov - 2017
Body System: Immune system
NHS England
RITUXIMAB (MabThera®) for the treatment of Systemic Lupus Erythematosus in adults
Date Posted: 15 - Nov - 2017
Body System: Immune system
Red
RITUXIMAB infusion in Rheumatoid Arthritis (RA)
Date Posted: 24 - May - 2017
Body System: Musculoskeletal system
Amber initiated
RIVAROXABAN 2.5mg tablets (Xarelto®▼) for Acute Coronary Syndrome
Date Posted: 24 - May - 2017
Body System: Cardiovascular system
Amber recommended
ROFLUMILAST (Daxas®▼)
Date Posted: 27 - Sep - 2017
Body System: Respiratory system
Grey
ROMIPLOSTIM subcutaneous injection (Nplate®)
Date Posted: 19 - May - 2016
Body System: Blood and blood-forming organs
Green
ROSUVASTATIN tablets
Date Posted: 31 - Jan - 2018
Body System: Cardiovascular system
Amber initiated
SACUBITRIL/VALSARTAN film-coated tablets (Entresto®▼)
Date Posted: 29 - Sep - 2016
Body System: Cardiovascular system
Amber recommended
SAFINAMIDE tablets (Xadago®▼)
Date Posted: 24 - May - 2017
Body System: Nervous system
Red
SARILUMAB solution for injection (Kevzara®▼)
Date Posted: 23 - Jul - 2018
Body System: Musculoskeletal system
Red
SECUKINUMAB in the management of Psoriasis
Date Posted: 27 - Jun - 2018
Body System: Skin
Red
SECUKINUMAB solution for injection (Cosentyx®▼) for ankylosing spondylitis
Date Posted: 02 - Nov - 2016
Body System: Musculoskeletal system
Red
SECUKINUMAB solution for subcutaneous injection (Cosentyx®▼) for Plaque Psoriasis
Date Posted: 29 - Jul - 2015
Body System: Skin
Black
SILK garments (Dermasilk®, Dreamskin®, Skinnies Silk®)
Date Posted: 11 - Apr - 2018
Body System: Skin
Red
Sodium Oxybate Oral Solution (Xyrem®)
Date Posted: 30 - Nov - 2016
Body System: Nervous system
NHS England
SOFOSBUVIR (Sovaldi®▼) for the treatment of Hepatitis C
Date Posted: 21 - Nov - 2017
Body System: Anti-infective
Black
SOLIFENACIN WITH TAMSULOSIN Modified-Release Tablets (Vesomni®)
Date Posted: 30 - Jul - 2014
Body System: Genito-urinary system
NHS England
STRIBILD®▼ (Tenofovir with cobicistat, elvitegravir, and emtricitabine) for the treatment of HIV
Date Posted: 21 - Nov - 2017
Body System: Anti-infective
Black
TAPENTADOL immediate release preparations (Palexia®)
Date Posted: 11 - Apr - 2018
Body System: Nervous system
Amber initiated
TAPENTADOL prolonged release tablets (Palexia® SR)
Date Posted: 27 - Jun - 2018
Body System: Nervous system
Grey
TELOTRISTAT film-coated tablets (Xermelo®▼)
Date Posted: 14 - Sep - 2018
Body System: Gastro-intestinal system
Black
THYROID EXTRACTS, DESICCATED
Date Posted: 28 - Jun - 2017
Body System: Endocrine System
Amber initiated
TICAGRELOR tablets (Brilique®)
Date Posted: 25 - Jan - 2017
Body System: Cardiovascular system
Grey
TIOTROPIUM inhalation (Spiriva Respimat®▼) for asthma in children and young people
Date Posted: 24 - May - 2018
Body System: Respiratory system
Green
TIOTROPIUM inhaler (Spiriva® Respimat®) in adults with asthma
Date Posted: 01 - Nov - 2018
Body System: Respiratory system
Red
TOCILIZUMAB (RoActemra®) in rheumatological conditions
Date Posted: 11 - Apr - 2018
Body System: Musculoskeletal system
Grey
TOFACITINIB film-coated tablets (Xeljanz®▼) for Psoriatic Arthritis
Date Posted: 19 - Jul - 2018
Body System: Musculoskeletal system
Red
TOFACITINIB film-coated tablets (Xeljanz®▼) for Rheumatoid Arthritis
Date Posted: 21 - Jun - 2018
Body System: Musculoskeletal system
Grey
TOFACITINIB film-coated tablets (Xeljanz®▼) for Ulcerative Colitis
Date Posted: 07 - Sep - 2018
Body System: Gastro-intestinal system
Black
TRAMADOL with DEXKETOPROFEN tablets (Skudexa)
Date Posted: 04 - Jun - 2018
Body System: Nervous system
Amber retained
TRIPTORELIN (Decapeptyl® SR)
Date Posted: 28 - Feb - 2018
Body System: Genito-urinary system
Black
ULIPRISTAL 5mg tablets (Esmya®) for uterine fibroids
Date Posted: 26 - Apr - 2018
Body System: Genito-urinary system
Red
USTEKINUMAB in the management of Psoriasis
Date Posted: 27 - Jun - 2018
Body System: Skin
Red
USTEKINUMAB injection (Stelara®) for Crohn’s disease
Date Posted: 06 - Jul - 2017
Body System: Gastro-intestinal system
Red
USTEKINUMAB injection (Stelara®) for Psoriatic Arthritis
Date Posted: 24 - May - 2017
Body System: Skin
Green
VORTIOXETINE tablets (Brintellix®▼)
Date Posted: 28 - Feb - 2018
Body System: Nervous system